If you are thinking about putting together a dietary formulation aimed at taking care of the needs of people who are involved in exercise training programs, and other regular athletic performances, you need to use one that is of good bioavailablity and free of tolerance problems or adverse effects. In the recent published study, abstracted below, Albionís Zinc (Bis)Glycinate Chelate was demonstrated to be a zinc form that more than meets these parameters.
As the current nutritional zinc intake frequently falls outside the Dietary Reference Intake (DRI) and as zinc is an essential trace mineral involved in the function of many enzymes, zinc supplementation has been recommended to prevent or treat the adverse effects of zinc deficiency. The aim of the present study was to compare the oral bioavailablity of zinc bis-glycinate (a new formulation) with zinc gluconate (reference formulation). A randomized, cross-over study was conducted in 12 female volunteers. The two products were administrated orally at the single dose of 15mg (7.5 mg X 2), with a 7-day wash-out period between the two tests. Serum concentrations (Figure 1) of zinc were assayed by a validated inductively coupled plasma optical emission spectrometry (ICPOES) method and C(max), T(max), and areasunder-the-curve (AUCs) were determined. The comparison between the two treatments was performed by comparing the C(max), AUC(t), and AUC(inf) using an analysis of variance followed by the calculation of the 90% confidence intervals of the ratio test/reference. Bis-glycinate administration was safe and well tolerated and bis-glycinate significantly increased the oral bioavailability of zinc (+43.4%) compared with the gluconate.